The reference site for Fludarabine

Fludarabine, sold under the brand name Fludara among others, is a chemotherapy medication used in the treatment of leukemia and lymphoma.

WHAT IS Fludarabine?

Fludarabine is a cancer (antineoplastic) medication. It is used to treat chronic lymphocytic leukemia (CLL), a type of blood cancer. It is more commonly known by its brand name, Fludara®.

Fludarabine belongs to the group of medicines called antimetabolites. These type of medications work by interfering with the genetic material (DNA) inside the cancer cells and prevent them from further dividing and growing into more cancer cells.

 

Brand Name(s): Fludara
CAS nº: 75607-67-9
(flu dah rah been)

 

Product Info

The sections below will provide you with more specific information and guidelines related to fludarabine and its correct use. Please read them carefully.

FDA Information

Fludarabine is FDA approved for the treatment of chronic lymphocytic leukemia that has stopped responding, or never responded, to previous therapies. It may also be used as therapy for patients with non-Hodgkin’s lymphoma or acute leukemia that has stopped responding to standard therapies.

Fludarabine has been available for use since the early 1990s. Please visit the official site of the FDA if you are interested in finding further information regarding this medication.

Why is this medication prescribed?

Fludarabine is a cancer (antineoplastic) medication. It is used to treat chronic lymphocytic leukemia (CLL), a type of blood cancer. It is marketed under the brand name Fludara®.

Fludarabine belongs to the group of medicines called antimetabolites. These type of medications work by interfering with the genetic material (DNA) inside the cancer cells and prevent them from further dividing and growing into more cancer cells.

Other uses for this medicine

Fludarabine has also been used to treat Hodgkin’s and non-Hodgkin’s lymphoma, cutaneous T-cell lymphoma, macroglobulinemic lymphoma, mycosis fungoides, and hairy cell leukemia.

However, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Fludarabine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with fludarabine depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Additionally, your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with fludarabine to monitor progress and side effects.

Skin accidentally exposed to fludarabine should be rinsed thoroughly with soap and warm water.

What special precautions should I follow?

BEFORE TAKING FLUDARABINE:

Tell your doctor if you have had any recent vaccinations, liver disease, kidney disease, bone marrow problems, or a history of lung or breathing problems. You may not be able to take fludarabine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Fludarabine can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with fludarabine. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

Skin accidentally exposed to fludarabine injection should be rinsed thoroughly with soap and warm water.

Fludarabine is in the FDA pregnancy category D. This means that fludarabine is known to cause birth defects in an unborn baby. Do not take fludarabine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Furthermore, it is not known whether fludarabine passes into breast milk. Do not take fludarabine without first talking to your doctor if you are breast feeding a baby.

What should I do if I forget a dose?

Contact your doctor if you miss a dose of fludarabine.

What side effects can this medication cause?

Possible side effects from fludarabine include:

fatigue
raised temperature
temporary effect on the bone marrow

Tell your doctor if any of these symptoms are severe or do not go away:

nausea, vomiting, diarrhea, or abdominal pain
loss of appetite
rash, itching or hives
tiredness
muscle pain
weakness

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives)
decreased bone marrow function and blood problems (extreme fatigue; unusual bruising or bleeding; black, bloody or tarry stools; or fever, chills, sore throat, or signs of infection)
chest pain, sudden shortness of breath, or a dry cough
blood in the urine
side (flank) pain

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Your healthcare provider will store fludarabine as directed by the manufacturer. If you are storing fludarabine, please follow the directions provided by your healthcare provider.

In case of an emergency/overdose

If for any reason an overdose of fludarabine is suspected, call local emergency services on 911 or contact your healthcare provider immediately.

Symptoms of a fludarabine overdose tend to be similar to side effects caused by the medication, although often more severe.

Product Images

PICTURES OF FLUDARABINE MEDICATION

Below you will find images and specific information on the principal types of fludarabine that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor

 

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